NEWMELAN DAY & NIGHT® by Dr. Eduardo Krulig is the synergistic combination of several assets, simultaneously blocking the different stages that are related in the formation of Melasma.NEWMELAN DAY & NIGHT acts in several stages of melanogenesis, inhibiting inflammatory processes, tyrosinase, the process of oxidation of tyrosine and the formation of melanin. It acts at the level of melanocytes, and melanosomes, superficial layers of the skin.

RECOMMENDATION:• Melasma;• Post-inflammatory hyperpigmentation;• Acanthosis nigricans;• Photo-aging and chrono-aging;• Opaque skin, without luminosity;• Post-acne hyperpigmentation;• Prevention and treatment of post-peeling hyperpigmentation.

WAY OF USE:Apply a small amount of the product on the entire facial surface according to professional criteria.

NEWMELAN PRO by Dr. Eduardo Krulig, is a perfect and powerful combination of anti-inflammatory, depigmenting actives, with potent antioxidant activity. Exclusive use in the office.The mask's assets are combined to allow a powerful control and inhibition of melanin synthesis, intervening in the pre-synthesis processes, directly inhibiting the tyrosinase enzyme, degranulating the intra-keratinocyte pigment and favoring the epidermis turnover and the elimination of pigmented cells.

RECOMMENDATION:• Melasma;• Post-inflammatory hyperpigmentation;• Acanthosis nigricans;• Photo-aging and chrono-aging;• Opaque skin, without luminosity;• Post-acne hyperpigmentation.

WAY OF USE:Apply the mask evenly and leave on for two to four hours. In case of the need for a maintenance process, the treatment can be carried out again after 6 months.

NEWMELAN TD by Dr. Eduardo Krulig. A solution for depigmenting treatments, transdermal release, for exclusive use in the office. It acts in the restructuring of the extracellular matrix and optimization in the treatment of hyperpigmentation. The synergistic combination of its assets allows it to generate a powerful antioxidant and anti-inflammatory activity, which leads to an inhibitory effect on the action of melanocyte synthesis in addition to inhibition of the enzyme tyrosinase. Depigmenting activity is generated by the acceleration of the phaeomelanin pathway and by the biochemical reduction of the deposited pigment.

RECOMMENDATION:• Melasma;• Post-inflammatory hyperpigmentation;• Acanthosis nigricans;• Photo-aging and chrono-aging;• Opaque skin, without luminosity;• Post-acne hyperpigmentation.

WAY OF USE:Apply the solution every 2 weeks, for a total of 6 weeks, if necessary.